Question: Where Do T Cells Go After Leaving The Thymus?

Where do T cells go after maturation?

Lymphoid progenitors which have developed from hematopoietic stem cells in the bone marrow migrate to the thymus to complete their antigen-independent maturation into functional T cells .

In the thymus, T cells develop their specific T cell markers, including TCR, CD3, CD4 or CD8, and CD2..

When T cells leave the thymus they can go to?

Naïve T cells exit the thymus and enter the bloodstream. If they remain in the bloodstream, then they will pass through the spleen. Naïve T cells can also enter lymph nodes by crossing high endothelial venules (HEVs). In these 2˚ lymphoid organs, naïve T cells encounter thousands of APCs.

What happens after T cell activation?

Helper CD4+ T cells Helper T cells become activated when they are presented with peptide antigens by MHC class II molecules, which are expressed on the surface of antigen-presenting cells (APCs). Once activated, they divide rapidly and secrete cytokines that regulate or assist the immune response.

When T cells leave the thymus they can go to quizlet?

– Mature T cells then leave the thymus in the blood and enter the secondary lymphoid organs, such as the spleen or lymph nodes.